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Characterization of some bacterial strains isolated from the Egyptian eastern and northern coastline
Marine microorganisms were considered to be important sources of marine bioactive compounds. The major objective of the ......
Natural products have been recognized as a major source of new drugs,but it is difficult to obtain effective compounds o......
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Control of Cucumber Whitefly and Spider Mite Under Greenhouse Conditions by some Medicinal Plants Ex
The insecticidal activities of the essential oils of five different medicinal plants (cumin,thyme,peppermint,fennel and ......
Rakicidin A is a cyclic depsipeptide that has exhibited unique growth inhibitory activity against chronic myelogenous le......
Discovery of Anti-Cancer Stem Cells Drug:Synthesis and Biological Evaluation of a Library of Natural
It is widely reported that cancer stem cells play a key role in carcinogenesis,cancer disease progression,relapse,and dr......
The natural product peiminine represses colorectal carcinoma tumor growth by inducing autophagic cel
Autophagy is a catabolic process,which is evolutionarily conservative in eukaryotic cells,that engulfs cellular long-liv......
Zebrafish as a vertebrate animal model is increasingly used for in vivo drug discovery and for assessing drug toxicity a......
Oridonin(1)is a complex ent-kaurane diterpenoid isolated from Isodon rubescens which displays remarkable antitumor activ......
Discovery of anti-cancer stem cells drug:synthesis and biological evaluation of a library of natural
It is widely reported that cancer stem cells play a key role in carcinogenesis,cancer disease progression,relapse,and dr......
Natural product compound 3c ameliorates brain inflammation and brain ischemic stroke via AMPK-mediat
OBJECTIVE Brain inflammation plays an important role in the pathophysiology of brain ischemic stroke, psychiatric and ne......
Csp3-Ⅰ bond,especially those with β-hydrogen atoms,are a class of challenging substrates for the palladium-catalyzed t......
Flavonoid quercetin protects the neurovascular unit in the5-35-induced amnesia model:consideration f
OBJECTIVE In the absence of a cure for Alzheimers disease (AD), development of preventative and therapeutical medication......
Autophagy is a conserved catabolic process,which functions in maintenance of cellular homeostasis in eukaryotic cells.Th......
Natural product inspired design and synthesis of molecular hybrids based on Largazole and Psammaplin
Since SAHA (2006),Belinostat (2014),Panobinostat (2015),Chidamide and Romidepsin (FK228,2010) were approved for the trea......
模拟自然界生物酶参与的精妙绝伦的化学转化是合成化学领域极具挑战性的课题。仿酶催化的阳离子环化反应是有机合成中极为有用的反......
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Natural product extracts have been found to provide a valuable source of molecular diversity which is complementary to t......
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Diastereomeric Resolution of 25R/S Steroidal Saponin Isomers from the Trigonella foenum-graecum Seed
Natural product-led drug discovery has made a strong come back in recent years.One of the key steps in natural product r......
Amino acid type amphoteric surfactants belong to green chemicals and have been used more and more extensively to many fi......
Practical Comparison of LC Columns Packed with Different Superficially Porous Particles for Separati
Commercial C18 columns packed with superficially porous particles of different size and shell thickness (Ascentis Expres......
A series of potential compounds of the isoprene chalcone structure skeleton synthesized with the nat
Androgen deprivation therapy(ADT),a backbone of therapy for patients with metastatic prostate cancer,is increasingly use......
Cinchonine and quinine are two cinchona alkaloids generously provided by nature[1,2] and their applications in chemistry......
Natural product has long been used in the medical field.As an important source of new drugs,natural product remains esse......
Chronic inflammation results from excessive pro-inflammatory signaling and the failure to resolve the inflammatory react......
Activator protein 1(AP-1)is a transcription factor that regulates a variety of protein-encoding genes,it is a partic......
Alkafoids are an important type of natural products,most of which are produced by plants and about one-third are pro......
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瘢痕是伤口自然愈合过程中一种正常的生理反应,但过度愈合会导致病理性瘢痕的生成。病理性瘢痕会影响皮肤美观及造成功能障碍等,使患......
由于新药研发耗资大、周期长、风险高,越来越多的学者把目光投向天然产物的研究. 中药成分蓝雪醌是一种天然的α-萘醌类化合物,主......
Objective: To establish the chemical profile, and to evaluate the antibacterial and modulatory activity of the ethanolic......
Major studies on the pharmacology of traditional herbs as well as active compounds have been introduced in this review o......